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Wham clusters the many candidate breakpoints and rounds their positions to the nearest tenth base pair. The position with the best read through support is claimed. In case the tender-clipped consensus sequence is usually aligned towards the putative breakpoint area using the Smith-Waterman algorithm, the breakpoint is more refined to the location i

The delicate-clipped sequences that overhang the breakpoint are collapsed into a consensus sequence using a numerous sequence alignment (MSA) furnished during the seqAn library [27]. Wham applies 3 filters towards the consensus sequences. Breakpoints are certainly not reported in instances exactly where consensus sequences are shorter than ten bp o

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